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Post-exposure prophylaxis
(or PEP)

is a way to prevent HIV infection after a possible recent exposure. It involves taking HIV medications as soon as possible (within 3 days) after a single high-risk event to stop HIV from making copies of itself and spreading throughout your body. Below, we share important information about PEP from CDC (Centers for Disease Control and Prevention):

PEP (post-exposure prophylaxis) means taking antiretroviral medicines (ART) after being potentially exposed to HIV to prevent becoming infected.

PEP should be used only in emergency situations and must be started within 72 hours after a recent possible exposure to HIV. If you think you’ve recently been exposed to HIV during sex or through sharing needles and works to prepare drugs or if you’ve been sexually assaulted,
 

Talk to the doctor about PEP right away.

WHAT IS PEP?

PEP stands for post-exposure prophylaxis. It means taking antiretroviral medicines (ART) after being potentially exposed to HIV to prevent becoming infected.
PEP must be started within 72 hours after a recent possible exposure to HIV, but the sooner you start PEP, the better. Every hour counts. If you’re prescribed PEP, you’ll need to take it once or twice daily for 28 days. PEP is effective in preventing HIV when administered correctly, but not 100%.

 

IS PEP RIGHT FOR ME?

If you’re HIV-negative or don’t know your HIV status, and in the last 72 hours you
1) Think you may have been exposed to HIV during sex (for example, if the condom broke),
2) Shared needles and works to prepare drugs (for example, cotton, cookers, water), or
3) Were sexually assaulted,

 

Talk to the doctor about PEP right away.

PEP should be used only in emergency situations and must be started within 72 hours after a recent possible exposure to HIV. It is not a substitute for regular use of other proven HIV prevention methods, such as pre-exposure prophylaxis (PrEP), which means taking HIV medicines daily to lower your chance of getting infected; using condoms the right way every time you have sex; and using only your own new, sterile needles and works every time you inject.

PEP is effective, but not 100%, so you should continue to use condoms with sex partners and safe injection practices while taking PEP. These strategies can protect you from being exposed to HIV again and reduce the chances of transmitting HIV to others if you do become infected while you’re on PEP.

 

WHEN SHOULD I TAKE PEP?

PEP must be started within 72 hours after a possible exposure. The sooner you start PEP, the better; every hour counts.
Starting PEP as soon as possible after a potential HIV exposure is important. Research has shown that PEP has little or no effect in preventing HIV infection if it is started later than 72 hours after HIV exposure. If you’re prescribed PEP, you’ll need to take it once or twice daily for 28 days.

DOES PEP HAVE ANY SIDE EFFECTS?

PEP is safe but may cause side effects like nausea in some people. These side effects can be treated and aren’t life-threatening.

愛滋病(HIV)藥物(PEP)

PEP的副作用

服用PEP藥時,有10%—30%的人會出現一些不同程度的副作用,最常見的是消化道毒副反應,包括噁心、嘔吐、無力等,還有的人會感覺頭暈、輕微腹瀉等。有的人還會出現肝功能的損害、貧血等。但事後預防性投藥(PEP)的副作用因人而異,並會在停止用藥後消失

使用PEP前敬請諮詢醫生意見。
由於PEP在香港供應數量有限,如閣下需要緊急療程,
請通過電子郵件與我們聯絡: info@emchk.com 或
致電 : (852) 6511 8000 

PEP注意事項

接受PEP藥物治療

  • 是否與HIV感染者/高危HIV感染者有性接觸或血液接觸
  • 需要留意肝腎功能是否正常
  • 有否感染梅毒、乙型肝炎、丙型肝炎等疾病

接受PEP藥物

  • 必需在暴露愛滋病病毒(HIV)後72小時內
  • 必需完成整個療程(28天)
  • 不應進行高危暴露

接受PEP藥物治療

  • 於整個療程後進行HIV測試

暴露前預防性投藥(PrEP)

暴露前預防性投藥 (pre-exposure prophylaxis, PrEP) 是一種用抗愛滋病病毒藥物減低非感染者在高度暴露的環境下感染愛滋病病毒風險的預防措施,下稱PrEP。PrEP的藥物成分是舒發泰(Truvada),是結合tenofovir及emtricitabine的複方。這兩種藥物是用來阻斷HIV病毒感染宿主的重要途徑。若持續服用PrEP來預防HIV,則血液中此藥物成分可阻止病毒進展到感染確立階段以及在人體內擴散。需注意的是,PrEP並不是疫苗,身體並不會因為使用PrEP而產生愛滋病病毒抗體,所以需要定期口服使用才有其預防效用。在發生性行為前服用一粒藥丸並不能有效阻隔愛滋病病毒。